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Modeling the 3D conformation of genomes /
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ISBN/ISSN：9781138500792 : 1138500798
中图号：Q343.1
题名：Modeling the 3D conformation of genomes / edited by Guido Tiana, Luca Giorgetti.
附加题名：Modeling the three-dimensional conformation of genomes
载体形态：xvi, 369 pages ; 25 cm.
丛编：Series in computational biophysics Series in computational biophysics.
附注：Includes bibliographical references and index.
内容附注：Preface -- Editor -- Contributors -- 1. Chromosome folding: contributions of chromosome conformation capture and polymer physics -- Part 1: First-Principle Models: 2. Modeling the functional coupling between 3D chromatin organization and epigenome -- 3. The strings and binders switch model of chromatin -- 4. Loop extrusion: a universal mechanism of chromosome organization -- 5. Predictive models for 3D chromosome organization: the transcription factor and diffusive loop extrusion models -- 6. Introducing supercoiling into models of chromosome structure -- 7. Structure and microrheology of genome organization: from experiments to physical modeling -- 8. Analysis of chromatin dynamics and search processes in the nucleus -- 9. Chromosome structure and dynamics in bacteria: theory and experiments -- Part 2: Data-Driven Models: 10. Restraint-based modeling of genomes and genomic domains -- 11. Genome structure calculation through comprehensive data integration -- 12. Modeling the conformational ensemble of mammalian chromosomes from 5C/Hi-C data -- 13. Learning genomic energy landscapes from experiments -- 14. Physical 3D modeling of whole genomes: exploring chromosomal organization properties and principles.
附加责任者：Tiana, G. (Guido), Giorgetti, Luca,
- GenomesGenomicsData processing.Technological innovations.
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